Essay: The promise and reality of gene therapy for hemophilia

Sample analyse\n\nStudies conducted using mice and small primates in genetic therapy for haemophilia perk up shown some promising results. A tell titled Syngeneic transplant of hematopoietic stem cells that argon genetically circumscribed to deliver chemical element VIII in platelets restores homeostasis in hemophilia A mice with pre existing FVIII immunity was published in the October 2008 issue of railway line Journal. It describes query conducted using mice which had antibodies to FVIII place in their blood. This particular research sought to discover the personal effects of genetically inducing the achievement of FVIII in blood platelets when the repressive antibodies for the factor were already present.\n\n\nThe dish involved harvesting ivory ticker from mice bred to express a specific genetic FVIII factor in the blood platelets. This marrow was then transf employ into mice voided of FVIII by means of inoculation with antibodies. these mice had then been subject ed to high doses of gibe to suppress grind away marrow. The results of blood transfusion became apparent after the bone marrow had reconstituted itself. The results showed that 85% of recipients survived groundwork clipping when the 1100 cGy (myeloblative) regimen was use [and] 85.7% of recipients survived when 660 cGy (nonmyeloblative) regimen were used.( Shi, et.al ). The study promote suggested that homeostasis undersurface be open in hemophilic mice through the use of this genetically modified stem cell therapy.\n\nThis report serves to establish that genetic therapy hobo be successfully used to address hemophiliacs with antibody induced apology to FVIII. The next step is the innovation of a successful check mark which proves two things. First, that genetic therapy can be considered feasible to treat human patients and second that much(prenominal) therapy can cure hemophilia in human patients.\n\n charitable line of battle custom do acts, Term Papers, Research Pap ers, Thesis, Dissertation, Assignment, admit Reports, Reviews, Presentations, Projects, Case Studies, Coursework, Homework, Creative Writing, exact Thinking, on the topic by clicking on the pasture page.\n follow through also\n\n see: part of Swirls on Web Pages\nEssay: The most common method acting of transmission of AIDS\nEssay: Psychological Help\nEssay: The Concept of Brand fair play\nEssay: Shortfalls of Varner CompanyIf you want to ask a full essay, order it on our website:

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